September 28, 2023
Basics of sequence similarity and homology searches
Sequence similarity and homology searches are crucial techniques in bioinformatics to study evolutionary relationships, infer function, and understand the structural…
Category: bioinformatics
September 28, 2023
Sequence alignment techniques (pairwise and multiple sequence alignment)
Section 1: Pairwise Sequence Alignment Definition and Purpose: Pairwise Sequence Alignment is the arrangement of two sequences to achieve maximum…
September 28, 2023
Exploring the Interplay of DNA, RNA, and Proteins in Bioinformatics
Introduction: Bioinformatics is a burgeoning field lying at the intersection of biology, computer science, mathematics, and engineering. It facilitates the…
September 28, 2023
Insights into Sequence and Structure Databases and Their Multidimensional Impact
I. Introduction A. Definition of Sequence and Structure Databases Sequence Databases and Structure Databases are specialized kinds of biological databases.…
September 28, 2023
An In-depth Exploration of Antibody Sequencing and Production Technologies
I. Introduction Delving into the intricate world of immunology, antibody sequencing stands as a cornerstone, unveiling the detailed arrangement of…
September 27, 2023
Comprehensive Guide to Bulk Homology Analysis: From Sequence Retrieval to Biological Interpretation
Performing homology analysis using BLASTP at bulk and then parsing the results into a table requires several steps, including fetching…
September 27, 2023
Comparative Genomic Analysis: A Step-by-Step Guide to Identifying and Comparing Human and Mouse Genes Using NCBI and Command-Line Tools
The biologist wants to compare human genes with mouse genes to identify common and unique genes between the two species.…
September 26, 2023
An Introductory Guide to Single-Cell Analysis for Biologists
Single-Cell Analysis Introduction: Single-cell analysis involves studying the transcriptomics, genomics, proteomics, and metabolomics at the single-cell level. This is in…
September 26, 2023
Bioinformatics database – A Step-by-Step Guide to Database Creation using MySQL and PHP
MySQL Installation: For Windows: Download MySQL Installer: Visit the MySQL official download page Download the MySQL Installer community version. Install…
September 26, 2023
Comprehensive Guide to Leveraging Docker for Bioinformatics: From Installation to Advanced Workflow Management
Running bioinformatics tools using Docker is a great way to maintain reproducibility and avoid issues with dependencies. Here is a…
September 26, 2023
Elucidating Circular RNA Sequences: A Comprehensive Guide to Utilizing circBase
Let’s use the gene “GNB1” as an example for the steps. Please note that the availability of results may vary,…
September 26, 2023
Guide to Installing, Running, and Analyzing MD Simulations with GROMACS: A Practical Approach with Python and R
Installing GROMACS On Linux: Update the package list: shellCopy code sudo apt update Install the necessary build dependencies: shellCopy code…
September 26, 2023
Bioinformatics Bash Scripting Tutorial: Processing and Analyzing FASTA Sequences
Bash scripting is crucial in bioinformatics for automating repetitive tasks and data processing. Below, I am providing a step-by-step guide,…
September 26, 2023
Automated Bioinformatics Analysis: A Comprehensive Bash Script Pipeline for Protein Analysis
A comprehensive bash script that does all of these tasks is quite extensive and complex, requiring integration of various bioinformatics…
September 26, 2023
Guide to Analyzing Protein and Nucleotide FASTA Sequences Using R: From Basics to Advanced Techniques
To perform analysis on protein and nucleotide FASTA sequences using R, you will need to install and load the appropriate…
September 26, 2023
The Role of Integrative Multi-Omics Analysis in Deciphering Biological Systems
Integrative multi-omics analysis is a rapidly advancing field, aiming to harness insights from the integration of multiple “omics” data types.…
September 26, 2023
A Comprehensive Bioinformatics Tutorial: Mastering Ligand-Protein Docking with AutoDock
Introduction: AutoDock is a suite of automated docking tools designed to predict how small molecules, such as substrates or drug…
September 25, 2023
Bioinformatics Approaches to Protein Structure Prediction, Ligand Interaction, and Drug Design: A Detailed Tutorial
1. Downloading Protein Sequence from Uniprot: a. Go to UniProt Type “Green Fluorescent Protein” or “P42212” in the search bar.…
September 24, 2023
A Comprehensive Guide to Python Programming for PDB Analysis in Bioinformatics
Step 1: Setting Up Python Installation Install Python: Download Python from Python’s official site. Follow the installation instructions for your…
September 24, 2023
Explorative Journey into Python for Bioinformatics: A Comprehensive Learning Path from Beginner to Advanced
Detailed Beginner Level Python Tutorial for Bioinformatics 1. Installing Python: Download Python from Python’s Official Site. For bioinformatics, it’s recommended…