Step-by-Step Guide to Downloading TCGA Data from GDC
The Genomic Data Commons (GDC) is the primary repository for The Cancer Genome Atlas (TCGA) data. This guide provides a…
Bioinformatics, AI, Genomics, Proteomics and Transcriptomics
The Genomic Data Commons (GDC) is the primary repository for The Cancer Genome Atlas (TCGA) data. This guide provides a…
Creating high-quality websites for bioinformatics applications requires a combination of robust backend frameworks, modern frontend libraries, and user-friendly design principles.…
Mapping SNPs to nearby genes is a common task in genomics, especially when studying the potential impact of non-coding variants.…
Principal Component Analysis (PCA) is a powerful tool for analyzing population structure and genetic variation using VCF (Variant Call Format)…
This guide provides a comprehensive approach to retrieving allele frequencies from the 1000 Genomes Project using various tools and programming…
Processing SFF and FastQ files efficiently is a common task in bioinformatics. Below is a step-by-step guide to efficiently view, analyze, clip ends, convert,…
In RNA-seq (and other sequencing technologies like whole-genome sequencing), the terms Read and Fragment are often used, and they have distinct meanings. Here’s a…
Here’s a step-by-step manual with recent tips, tricks, and some of the best bioinformatics one-liners for common tasks. These one-liners…
Mapping SNPs to pathways and diseases is a complex but crucial task in genomics research. Here are some of the…
Phylogenetic analysis of whole genomes is a complex but powerful approach to understanding evolutionary relationships among species. Below is a…
In bioinformatics, the tasks can range from simple data processing to complex data integration and interpretation. Below is a breakdown…
Establishing a new bioinformatics unit, especially in an academic or research institution, requires careful planning and consideration of various factors,…
Counting the number of N characters (ambiguous bases) in FASTA sequences is a common task in bioinformatics. Below are several methods to…
Extracting specific sequences from a large FASTA file is a common task in bioinformatics. Below are several methods to achieve…
Choosing the right human reference genome is a critical decision in bioinformatics, especially for tasks like alignment, variant calling, and…
Bioinformatics is a field that combines biology, computer science, and statistics, and while it is incredibly rewarding, it comes with…
Entering the field of bioinformatics can be both exciting and overwhelming. Here are some key insights, tips, and advice that…
Bioinformatics is a highly interdisciplinary field, and the tools and techniques you need to master depend on your specific area…
1. Understanding Paired-End Sequencing Definition: Paired-end sequencing involves sequencing both ends of a DNA fragment, providing two reads (forward and reverse)…
Bioinformatics is a rapidly evolving field, driven by advancements in technology, data generation, and interdisciplinary research. This step-by-step manual provides…