January 10, 2025
Step-by-Step Guide: Downloading the PAM50 Gene Set
The PAM50 gene set is a widely used panel of 50 genes for classifying breast cancer subtypes. While the gene…
Category: CRISPR
January 10, 2025
Step-by-Step Guide to Downloading TCGA Data from GDC
The Genomic Data Commons (GDC) is the primary repository for The Cancer Genome Atlas (TCGA) data. This guide provides a…
January 10, 2025
Step-by-Step Guide to Mapping SNPs to Genes within Window
Mapping SNPs to nearby genes is a common task in genomics, especially when studying the potential impact of non-coding variants.…
January 10, 2025
Step-by-Step Guide to Performing PCA from VCF Files
Principal Component Analysis (PCA) is a powerful tool for analyzing population structure and genetic variation using VCF (Variant Call Format)…
January 9, 2025
DNA Compression Algorithms
DNA compression is a specialized area of bioinformatics that aims to reduce the storage size of DNA sequences while preserving…
January 9, 2025
Which Human Reference Genome Should I Use?
Choosing the right human reference genome is a critical decision in bioinformatics, especially for tasks like alignment, variant calling, and…
January 9, 2025
Step-by-Step Manual: Future Directions in Bioinformatics
Bioinformatics is a rapidly evolving field, driven by advancements in technology, data generation, and interdisciplinary research. This step-by-step manual provides…
January 9, 2025
Step-by-Step Guide to Understanding Different Bioinformatics Positions
Bioinformatics is a multidisciplinary field that combines biology, computer science, and statistics. As the field grows, so do the variety…
January 9, 2025
Step-by-Step Manual to Find Disease-Associated SNPs
This guide provides the latest tools, databases, and tips to identify disease-associated SNPs, including associated PMIDs, case/control numbers, and population…
January 9, 2025
Step-by-Step Manual: How Bioinformatics Has Improved Over Time
Bioinformatics has evolved significantly over the past few decades, driven by advancements in sequencing technologies, computational power, and the development…
January 9, 2025
Step-by-Step Manual: Why and How to Use Galaxy for Bioinformatics
Galaxy is a powerful, web-based platform for data-intensive biomedical research. It provides an accessible interface for bioinformatics analyses, making it…
December 29, 2024
Survival Analysis with Gene Expression in Bioinformatics: A Beginner’s Guide
Introduction Survival analysis is a powerful statistical tool used in bioinformatics to understand the relationship between gene expression data and…
December 21, 2024
CRISPR/Cas Systems and Anti-CRISPR Proteins
Introduction: The CRISPR/Cas Revolution The CRISPR/Cas system, a groundbreaking genome-editing tool, has transformed biomedical research by enabling precise genetic modifications.…
December 20, 2024
CRISPR and the Future of Cancer Treatment
CRISPR-Cas9 Gene Editing in Cancer Treatment The CRISPR-Cas9 gene-editing technology has emerged as a groundbreaking tool with the potential to…
December 19, 2024
Empowering Genomics Education: Data Literacy in Genome Research
In a world increasingly dominated by data, equipping students with the skills to analyze and interpret complex datasets is more…
December 19, 2024
CRISPR-DIPOFF: A Deep Learning Breakthrough in Off-Target Predictions for CRISPR-Cas9
Revolutionizing Genome Editing with CRISPR-Cas9 The advent of CRISPR-Cas9 technology has transformed the landscape of genome editing, offering unparalleled precision…
December 18, 2024
Drug Repurposing: A Genomic Approach
Genomic Drug Repurposing: Revolutionizing the Search for New Treatments In the world of modern medicine, the process of developing new…
December 18, 2024
IT-Enabled Precision Medicine and Genomics
The healthcare industry is undergoing a revolutionary transformation, transitioning from traditional, one-size-fits-all treatments to a more individualized approach known as…
October 11, 2024
Integrating CRISPR-Cas9 into Undergraduate Research to Teach Fundamental Bioinformatics Techniques
The rapid evolution of CRISPR-Cas9 technology has transformed the landscape of genetic research and molecular biology. As a groundbreaking tool…
October 10, 2024
Comprehensive Bioinformatics Tools for CRISPR/Cas9 Design and Analysis
CRISPR/Cas9 technology has revolutionized genome editing, enabling precise modifications of genetic material in a wide range of organisms. To facilitate…