Category: Guides

Bioinformatics is a data-driven field that requires efficient management of time and resources to prevent unnecessary delays in analysis. Many…

Introduction In bioinformatics, working with genomic data often involves handling coordinates that represent positions in a sequence, such as nucleotides…

As a bioinformatician, it’s crucial to be aware of common mistakes that can impact data quality, analysis outcomes, and the…

Visualizing genomic feature data is crucial for understanding complex biological processes, identifying patterns, and deriving insights from genomic data. This…

Creating multiple histograms in a single plot is a common requirement in data visualization, particularly for comparative analysis. This guide…

Translation of RNA sequences to protein sequences is a fundamental task in bioinformatics. This process involves converting the codons (three-base…

Introduction to Minor Allele Frequency Definition: Minor allele frequency (MAF) is the proportion of the second most common allele (the…

ntroduction Counting sequences in a FASTQ.GZ file is a common task in bioinformatics for verifying data integrity, ensuring proper preprocessing,…

Heatmaps are essential tools for visualizing complex data, such as gene expression, in an intuitive and comprehensible manner. They provide…

This guide is designed to help beginners understand Synonymous and Non-Synonymous Single Nucleotide Polymorphisms (SNPs), how to distinguish between them,…

Introduction: In bioinformatics, BAM files are essential for storing aligned sequencing data, typically in the Binary Alignment/Map format. Sorting BAM…

1. Introduction: In bioinformatics, when performing read alignment (typically with tools like BWA, Bowtie, or HISAT2), we encounter two common…

Converting Affymetrix probes to gene IDs is an essential step in analyzing gene expression data derived from Affymetrix microarrays. It…

Introduction A comprehensive database of tumor suppressors and oncogenes is a crucial resource for cancer research. These databases provide insights…

Converting SAM (Sequence Alignment/Map) files to BAM (Binary Alignment/Map) format is a crucial task in bioinformatics, particularly in next-generation sequencing…

VCF (Variant Call Format) files are widely used in bioinformatics to store genomic data, particularly for representing variant information such…

Microarray data analysis is an essential task in bioinformatics, often used to examine gene expression patterns. Bioconductor, an open-source software…

Whole Exome Sequencing (WES) is a powerful tool for understanding genetic variations within coding regions of the genome. This pipeline…

Introduction to Coverage Calculation Coverage, in the context of genome sequencing, refers to how many times a particular base or…

This guide aims to help you evaluate whether pursuing a Master’s in Bioinformatics (MSc) will benefit your career prospects, especially…